The Original Enterprise was commissioned in the year 2245.  The Original Enterprise is the original ship to be used in the Star Trek show, and its Captain during the original Star Trek series was Captain Kirk.  The ship had a few other captain before captain Kirk, some of them were, Captain Pike, and Captain Robert April.  The Original Enterprise was destroyed in the year 2285 on the Genesis Planet.
The Enterprise-A is the second ship to have the Enterprise name, and it was launched in the year 2286.  The Enterprise-A was retired under the command of Captain Kirk in the year 2293.
Captain James T. Kirk was the Captain of two star ships to bear the name of Enterprise.  He commanded the Original Enterprise and the Enterprise-A.  He is assigned to a 5 year mission to explore uncharted regions of space.
Spock it the Volcan science officer of the star ship Enterprise.  Raised as a Volcan Spock, who's real name is to hard to prononce, only sees things in a logical manner, even though he is half human and half Volcan.  Spock's logical views create conflict between him and Dr. McCoy, the ship's doctor.
Dr. Lenard McCoy, otherwise known as "Bones" is the Enterprise's  doctor.  He always seems to disagree with Spock's logical views on life, more commonly following his heart, and his morals.
Montgomery Scott is the head of engineer on the Enterprise.  He is the Scottish engineer who is so often pushed for more power from the engines.
Uhura is a Lieutenant on the bridge of the Enterprise.  Uhura doesn't have a large role on Star Trek and mainly seems to only be there to work the communications systems.  So little is known of Uhura, nobody even knows her full name.
Hikaru Sulu is also a Lieutenant on the Enterprise.  Sulu, as Captain Kirk often calls him to shorten his name, is a helmsman.  Sulu isn't a mian character like Captain Kirk, Spock, or Dr. McCoy, but never the less he is an important one.
Pavel Chekov appears in the second season of Star Trek. Chekov is the Russian Helmsman that also doesn't play a large role.

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